
GermGuardian FLT5250PT
Score: 88/100
Honeywell HRF-R1
Score: 85/100Rankings

The GermGuardian FLT5250PT is a high-capacity True HEPA replacement filter featuring anti-microbial Pet Pure treatment to inhibit mold and bacteria. It offers 99.97% filtration efficiency at 0.1 microns with a large 13.0 sq ft surface area. It is best suited for pet owners and allergy sufferers needing extended filter freshness.

The Honeywell True HEPA Replacement Filter (HRF-R1) is an OEM filter designed for specific Honeywell air purifier series, capturing 99.97% of particles at 0.3 microns. It requires annual replacement and may necessitate purchasing multiple units per machine, which increases overall cost. Ideal for allergy sufferers owning compatible Honeywell units who prioritize warranty compliance.
| Attribute | ![]() | ![]() |
|---|---|---|
6 months | 12 monthsbest | |
99.97 percentbest | 99.97 percentbest | |
| ↓ lower better | 0.1 micronsbest | 0.3 microns |
3best | — | |
| ↓ lower better | 0.5 lbs | 0.25 lbsbest |
1best | 1best |
Click an attribute name to sort · Green = best, red = worst (relative to this comparison)
| Attribute | ![]() | ![]() |
|---|---|---|
Compatibility & Fit(1) | ||
Compatible Models | AC5250PT, AC5000E, AC5300B, AC5350B, AC5350W, AP2800CA, BXAP250, IAP-GG-125 | HPA-090, HPA-100, HPA200, HPA300 Series |
Maintenance & Lifespan(1) | ||
Replacement Interval (months) | 6 months | 12 months |
Physical & Packaging(2) | ||
Weight (lbs) | 0.5 lbs | 0.25 lbs |
Dimensions | 1.75 x 19.25 x 4.75 | 1.65 x 10.32 x 6.69 |
Filtration Performance(3) | ||
Minimum Particle Size Captured (microns) | 0.1 microns | 0.3 microns |
Activated Carbon Filter | true | false |
Target Contaminants | dust, pollen, pet dander, mold spores, odor-causing bacteria | pollen, pet dander, dust, mold spores, smoke, dust mite debris |

Products in the top-left offer the best value (high score, low price).

Professional reviewers highlight superior filtration capacity and the key differentiator of anti-microbial Pet Pure treatment for extended freshness.
Everyday users express strong satisfaction with pet dander management and odor reduction, appreciating the extended freshness from anti-microbial treatment.

“I did not understand that I needed THREE filters! ... replacement filters will run you more than half the purchase”




Professional reviewers and editors lack dedicated reviews for these replacement filters.
Everyday consumers generally praise the filters for working as expected in reducing allergens and providing reliable performance when paired with Honeywell units.